Similarities and differences of X and Y chromosome homologous genes , SRY and SOX 3 , 1 in regulating the renin - angiotensin system promoters

Similarities and differences of X and Y chromosome homologous genes, SRY and SOX3, 1 in regulating the renin-angiotensin system promoters. 2 Fabiano C. Araujo1, Amy Milsted2, Ingrid K. M. Watanabe3, Helen L. Del Puerto1, Robson 3 A. S. Santos4, Jozef Lazar5,6, Fernando M. Reis1, Jeremy W. Prokop5,6 4 National Institute of Science and Technology in Molecular Medicine and Department of 5 Obstetrics and Gynecology, School of Medicine, Federal University of Minas Gerais, Belo 6 Horizonte, MG 30130-100 Brazil 7 Department of Biology, The University of Akron, Akron, OH 44325 USA 8 Nephrology Division, Department of Medicine, Federal University of Sao Paulo, Sao Paulo, SP 9 04023-900 Brazil 10 Departamento de Fisiologia e Biofísica, Instituto de Ciências Biológicas, Federal University of 11 Minas Gerais, Belo Horizonte, MG 31270-901 Brazil 12 Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI 53226 13 USA 14 Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226 USA 15 Abbreviated title: SOX3 and SRY regulate the renin-angiotensin system 16 To whom correspondence should be addressed: Jeremy W. Prokop, Human and Molecular 17 Genetics Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 18 USA, Tel.: (414) 955-8808; Fax: (414) 456-6516; E-mail: [email protected] 19 20 Articles in PresS. Physiol Genomics (March 10, 2015). doi:10.1152/physiolgenomics.00138.2014